Author Schuberth, Ingrid

• 2013 | Journal Article
  ​ ​ChemInform Abstract: Synthesis and Biological Evaluation of a Novel Acronycine/Duocarmycin Hybrid Natural Product.​
  Tietze, L. F.; Heins, A.; Reiner, J. R.; Duefert, S.-C. & Schuberth, I.​ (2013) 
  ChemInform, 44(16) pp. no​-no​.​ DOI: https://doi.org/10.1002/chin.201316191 
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• 2013 | Journal Article
  ​ ​The Two Faces of Potent Antitumor Duocarmycin-Based Drugs: A Structural Dissection Reveals Disparate Motifs for DNA versus Aldehyde Dehydrogenase1 Affinity​
  Wirth, T.; Pestel, G. F.; Ganal, V.; Kirmeier, T.; Schuberth, I.; Rein, T. & Tietze, L. F. et al.​ (2013) 
  Angewandte Chemie International Edition, 52(27) pp. 6921​-6925​.​ DOI: https://doi.org/10.1002/anie.201208941 
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• 2013 | Journal Article
  ​ ​Photoactivatable Prodrugs of Highly Potent Duocarmycin Analogues for a Selective Cancer Therapy​
  Tietze, L. F.; Mueller, M.; Duefert, S.-C.; Schmuck, K. & Schuberth, I.​ (2013) 
  Chemistry - A European Journal, 19(5) pp. 1726​-1731​.​ DOI: https://doi.org/10.1002/chem.201202773 
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• 2012 | Journal Article
  ​ ​SYNTHESIS AND BIOLOGICAL EVALUATION OF A NOVEL ACRONYCINE/DUOCARMYCIN HYBRID NATURAL PRODUCT​
  Tietze, L. F.; Heins, A.; Reiner, J. R.; Duefert, S.-C. & Schuberth, I.​ (2012) 
  Heterocycles, 86(1) pp. 425​-433​.​ DOI: https://doi.org/10.3987/COM-12-S(N)37 
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• 2012 | Journal Article
  ​ ​Synthesis, Biological Evaluation, and Live Cell Imaging of Novel Fluorescent Duocarmycin Analogs​
  Tietze, L. F.; Behrendt, F.; Pestel, G. F.; Schuberth, I. & Mitkovski, M.​ (2012) 
  Chemistry & Biodiversity, 9(11) pp. 2559​-2570​.​ DOI: https://doi.org/10.1002/cbdv.201200289 
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• 2011 | Journal Article
  ​ ​Synthesis and Biological Evaluation of Prodrugs Based on the Natural Antibiotic Duocarmycin for Use in ADEPT and PMT​
  Tietze, L. F.; Schmuck, K.; Schuster, H. J.; Mueller, M. & Schuberth, I.​ (2011) 
  Chemistry - A European Journal, 17(6) pp. 1922​-1929​.​ DOI: https://doi.org/10.1002/chem.201002798 
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• 2010 | Journal Article
  ​ ​ChemInform Abstract: Highly Selective Glycosylated Prodrugs of Cytostatic CC-1065 Analogues for Antibody-Directed Enzyme Tumor Therapy.​
  Tietze, L. F.; Herzig, T.; Fecher Anja, F. A.; Haunert, F. & Schuberth, I.​ (2010) 
  ChemInform, 33(4) pp. no​-no​.​ DOI: https://doi.org/10.1002/chin.200204251 
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• 2010 | Journal Article
  ​ ​ChemInform Abstract: A Comprehensive View on 4-Methyl-2-quinazolinamine, a New Microbial Alkaloid from Streptomyces of TCM Plant Origin.​
  Volmar, D.; Thorn, A.; Schuberth, I. & Grond, S.​ (2010) 
  ChemInform, 41(1) pp. no​-no​.​ DOI: https://doi.org/10.1002/chin.201001204 
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• 2010 | Journal Article
  ​ ​Synthesis of the first spacer containing prodrug of a duocarmycin analogue and determination of its biological activity​
  Schuster, H. J.; Krewer, B.; von Hof, J. M.; Schmuck, K.; Schuberth, I.; Alves, F.   & Tietze, L. F.​ (2010) 
  Organic & Biomolecular Chemistry, 8(8) pp. 1833​-1842​.​ DOI: https://doi.org/10.1039/b925070k 
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• 2010 | Journal Article
  ​ ​Glycosidic Prodrugs of Highly Potent Bifunctional Duocarmycin Derivatives for Selective Treatment of Cancer​
  Tietze, L. F. ; von Hof, J. M.; Mueller, M.; Krewer, B. & Schuberth, I.​ (2010) 
  Angewandte Chemie International Edition, 49(40) pp. 7336​-7339​.​ DOI: https://doi.org/10.1002/anie.201002502 
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• 2009 | Journal Article | 
  ​ ​Determination of the Biological Activity and Structure Activity Relationships of Drugs Based on the Highly Cytotoxic Duocarmycins and CC-1065​
  Tietze, L. F.; Krewer, B.; von Hof, J. M.; Frauendorf, H. & Schuberth, I.​ (2009) 
  Toxins, 1(2) pp. 134​-150​.​ DOI: https://doi.org/10.3390/toxins1020134 
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• 2009 | Journal Article
  ​ ​CD-Spectroscopy As a Powerful Tool for Investigating the Mode of Action of Unmodified Drugs in Live Cells​
  Tietze, L. F.; Krewer, B.; Major, F. & Schuberth, I.​ (2009) 
  Journal of the American Chemical Society, 131(36) pp. 13031​-13036​.​ DOI: https://doi.org/10.1021/ja902767f 
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• 2009 | Journal Article | 
  ​ ​A comprehensive view on 4-methyl-2-quinazolinamine, a new microbial alkaloid from Streptomyces of TCM plant origin​
  Vollmar, D.; Thorn, A.; Schuberth, I. & Grond, S.​ (2009) 
  The Journal of Antibiotics, 62(8) pp. 439​-444​.​ DOI: https://doi.org/10.1038/ja.2009.68 
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• 2009 | Journal Article
  ​ ​Synthesis and Biological Studies of Different Duocarmycin Based Glycosidic Prodrugs for Their Use in the Antibody-Directed Enzyme Prodrug Therapy​
  Tietze, L. F.; Schuster, H. J.; Krewer, B. & Schuberth, I.​ (2009) 
  Journal of Medicinal Chemistry, 52(2) pp. 537​-543​.​ DOI: https://doi.org/10.1021/jm8009102 
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• 2008 | Journal Article
  ​ ​Duocarmycin-based prodrugs for cancer prodrug monotherapy​
  Tietze, L. F.; Schuster, H. J.; Schmuck, K.; Schuberth, I. & Alves, F. ​ (2008) 
  Bioorganic & Medicinal Chemistry, 16(12) pp. 6312​-6318​.​ DOI: https://doi.org/10.1016/j.bmc.2008.05.009 
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• 2008 | Journal Article
  ​ ​Asymmetric Synthesis and Biological Evaluation of Glycosidic Prodrugs for a Selective Cancer Therapy​
  Tietze, L. F.; von Hof, J. M.; Krewer, B.; Mueller, M.; Major, F.; Schuster, H. J. & Schuberth, I. et al.​ (2008) 
  ChemMedChem, 3(12) pp. 1946​-1955​.​ DOI: https://doi.org/10.1002/cmdc.200800250 
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• 2008 | Journal Article | 
  ​ ​Synthesis and biological evaluation of a novel pentagastrin-toxin conjugate designed for a targeted prodrug monotherapy of cancer​
  Tietze, L. F.; Panknin, O.; Krewer, B.; Major, F. & Schuberth, I.​ (2008) 
  International Journal of Molecular Sciences, 9(5) pp. 821​-837​.​ DOI: https://doi.org/10.3390/ijms9050821 
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• 2007 | Journal Article
  ​ ​Synthesis of highly functionalized anthraquinones and evaluation of their antitumor activity​
  Tietze, L. F.; Gericke, K. M. & Schuberth, I.​ (2007) 
  European Journal of Organic Chemistry,(27) pp. 4563​-4577​.​ DOI: https://doi.org/10.1002/ejoc.200700418 
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• 2007 | Journal Article
  ​ ​Novel strategies for the synthesis of anthrapyran antibiotics: discovery of a new antitumor agent and total synthesis of (S)-espicufolin​
  Tietze, L. F.; Gericke, K. M.; Singidi, R. R. & Schuberth, I.​ (2007) 
  Organic & Biomolecular Chemistry, 5(8) pp. 1191​-1200​.​ DOI: https://doi.org/10.1039/b700838d 
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• 2007 | Journal Article
  ​ ​Selective treatment of cancer: Synthesis, biological evaluation and structural elucidation of novel analogues of the antibiotic CC-1065 and the duocarmycins​
  Tietze, L. F.; Major, F.; Schuberth, I.; Spiegl, D. A.; Krewer, B.; Maksimenka, K. & Bringmann, G. et al.​ (2007) 
  Chemistry - A European Journal, 13(16) pp. 4396​-4409​.​ DOI: https://doi.org/10.1002/chem.200700113 
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